Body Composition & Sarcopenia Index DEXA SCAN |
Dual-Energy X-Ray Absorptiometry (DEXA): Visceral Adipose Tissue (VAT) mass/volume, Appendicular Lean Mass Index (ALMI), total fat-free mass, and bone mineral density (BMD). |
AT LEAST QUARTERLY T0, Q1, Q2, Q3, Q4 |
Quantify visceral fat reduction and skeletal muscle restoration countering post-separation sarcopenia and metabolic syndrome. |
Cardiopulmonary & Mitochondrial Capacity VO2 MAX & RMR |
Direct gas-exchange peak oxygen uptake (VO2 max), ventilatory thresholds (VT1/VT2), substrate oxidation (fat vs. carbohydrate crossover), and Resting Metabolic Rate (RMR). |
AT LEAST QUARTERLY T0, Q1, Q2, Q3, Q4 |
Measure cardiopulmonary fitness, burn-pit pulmonary resilience, and cellular aerobic efficiency under Pillar (b). |
Glycemic Control & Insulin Sensitivity CGM + HOMA-IR |
Continuous Glucose Monitoring (CGM) 14-day ambulatory profiles, fasting plasma glucose, fasting serum insulin, HOMA-IR index, and HbA1c. |
QUARTERLY + CONTINUOUS Lab panels quarterly; CGM per cohort phase |
Detect and reverse early-stage insulin resistance, dysglycemia, and Type 2 diabetes mellitus (T2DM) progression under Pillar (a). |
Neuroendocrine, HPA & Thyroid Axis FULL HORMONE PANEL |
Total & free testosterone, SHBG, estradiol, LH, FSH, diurnal cortisol / DHEA-S (HPA axis), TSH, free T3, free T4, reverse T3, and IGF-1. |
AT LEAST QUARTERLY T0, Q1, Q2, Q3, Q4 |
Characterize HPA/HPG-axis disruption and thyroid dysregulation following chronic operational stress and blast TBI exposure. |
Systemic Inflammation & Cardiometabolic Risk hs-CRP • IL-6 • CMP |
High-sensitivity C-Reactive Protein (hs-CRP), Interleukin-6 (IL-6), homocysteine, ApoB, NMR lipid profile, hepatic enzymes (AST, ALT, GGT for NAFLD), and complete blood count. |
AT LEAST QUARTERLY T0, Q1, Q2, Q3, Q4 |
Track resolution of chronic systemic and vascular inflammation associated with toxic exposures and metabolic dysfunction. |
Autonomic Nervous System & Sleep Telemetry HRV & SLEEP ARCHITECTURE |
Nocturnal Heart Rate Variability (RMSSD), resting heart rate, respiratory rate, sleep latency/efficiency, and validated veteran symptom inventories. |
CONTINUOUS + QUARTERLY Daily wearable telemetry; quarterly clinical synthesis |
Quantify parasympathetic recovery and HPA-axis stabilization across Pillar (c) regenerative recovery protocols. |